Karen Resseguie-Vickstrom, BSN, BBA, MBA

Diabetes Insipidus

Tags: ADH DI Diabetes Insipidus vasopressin

Diabetes Insipidus (DI) is a deficiency response to the antidiuretic hormone (ADH) also known as vasopressin. There are two types of vasopressin (V) receptors known as V1 and V2 in which the V1 receptors located in the vascular smooth muscles cause vasoconstriction whereas V2 receptors located on the tubular cells of the cortical collecting duct control the reabsorption of water via the kidneys. DI effects the renal mechanisms of the water reabsorption which is particularly imperative for maintaining body fluid osmolality. Edification that medication management is available in conjunction with readily accessible liquids at all times to replenish the enormous losses that occur through urination in addition to enforcement that this disease can easily turn to life threatening if not managed properly.